Document Type

Paper- Restricted to Campus Access

Publication Date

4-21-2020

Faculty Mentor

April Carpenter

Abstract

Force transducers are used to measure the force of muscle contraction after electrical stimulation. Here, we attempted to use relatively inexpensive materials to produce data from a force transducer ex vivo. After cervical dislocation of the mouse, the tibialis anterior was isolated and the leg was cut at the distal femur. The proximal tibia and fibula were removed so that the tibialis anterior was left attached to the patella. Using a 4.0 suture, a box knot was tied on the distal tendon of the tibialis anterior. The suture was used to attach the muscle to the force transducer and position the muscle for electrical stimulation. After isolating the tibialis anterior, the force of contraction was recorded. We were successful in attaching the muscle to the force transducer and recording reproducible data. We plan to use this technique to determine how different treatments restore normal muscle force following injury.

Comments

Presented as part of the Ursinus College Celebration of Student Achievement (CoSA) held April 23 – April 30, 2020.

The downloadable file is an audio commentary with a length of 1:13.

A poster with research findings is available here.

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