Document Type

Paper- Restricted to Campus Access

Publication Date

4-29-2026

Faculty Mentor

April Carpenter

Abstract

Glycogen storage in skeletal muscle is essential for maintaining energy availability during periods of increased metabolic demand, such as exercise and recovery from injury. This study investigates whether cryotherapy following muscle injury affects the ability of skeletal muscle to replenish glycogen stores. We also examined whether there is a difference between a single cryotherapy session and repeated sessions. Twelve mice (n = 4 per group) were assigned to three groups: no injury with cryotherapy, injury with one cryotherapy session, and injury with three days of cryotherapy. One tibialis anterior muscle was injected with barium chloride to chemically induce injury, while the contralateral muscle was injected with sodium chloride as a control. Cryotherapy was applied for 15 minutes per session, and muscle and liver tissues were collected 14 days post-injury. Glycogen content was quantified using a glycogen assay to assess metabolic recovery. This study aims to determine whether cryotherapy alters glycogen stores following muscle injury.

Comments

Presented as part of the Ursinus College Celebration of Student Achievement (CoSA) held April 29, 2026.

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