Submission Date
7-19-2024
Document Type
Paper- Restricted to Campus Access
Department
Chemistry
Faculty Mentor
Samantha Wilner
Project Description
Lipid micelles can be used to deliver hydrophobic pharmaceuticals in the bloodstream; however, micelles are inherently unstable because they require a large concentration of lipid to form, and they interact with serum proteins in the blood, causing them to disassemble. To prevent destabilization, we have covalently modified lipid micelles with DNA, with the goal of developing a micelle-based drug delivery system.
Recommended Citation
Roedema, Sophia, "Effects of DNA Interactions on the Assembly and Stability of Oligonucleotide-Lipid Nanoparticles" (2024). Chemistry Summer Fellows. 54.
https://digitalcommons.ursinus.edu/chem_sum/54
Restricted
Available to Ursinus community only.
Comments
Presented during the 26th Annual Summer Fellows Symposium, July 19, 2024 at Ursinus College.