One-Pot Synthesis of Fluorescent Rhodols Through a Smiles Rearrangement

Author

Julia Shoemaker, Ursinus CollegeFollow

Submission Date

7-22-2022

Document Type

Paper- Restricted to Campus Access

Department

Chemistry

Faculty Mentor

Ryan Walvoord

Comments

Presented during the 24th Annual Summer Fellows Symposium, July 22, 2022 at Ursinus College.

Project Description

A library of fluorescent rhodols through a one pot synthesis under mild conditions without the use of precious metals. The method was optimized via 1H NMR monitoring by testing several reaction variables. The optimized conditions were applied to fluorescein derivatives to prepare a series of N-alkyl rhodols and the products were characterized. Application and derivatization to related fluorophores is discussed.

Recommended Citation

Shoemaker, Julia, "One-Pot Synthesis of Fluorescent Rhodols Through a Smiles Rearrangement" (2022). Chemistry Summer Fellows. 45.
https://digitalcommons.ursinus.edu/chem_sum/45