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Carbon nanotubes serve as unique nanopore conduits due to their molecular selectivity. In this study we examine the transport of the neurologically relevant molecules acetylcholine, choline, and dopamine through a 1 nm-diameter 1.1-mm long single walled carbon nanotube (SWNT). The pore-blocking threshold voltages were 700 mV, 600 mV, and 500 mV for choline, acetylcholine, and dopamine, respectively. The dwell times for both acetylcholine and choline decrease with increasing voltage which is consistent for the proposed model for these ions. The average dwell times for choline and acetylcholine at 1000mV were 59.59607 ms and 61.96095 ms respectively. The average pore-blocking current (PBC) for choline at 1000 mV was 0.01024 nA and the average PBC for acetylcholine at 1000 mV was 0.023393 nA. At the time of submission of this abstract dopamine data was still undergoing analysis and the results of analysis will be presented in final presentation. Our results show that these three neurotransmitters do transport through a SWNT and the properties can be studied.
Baird, David, "Transport of Neurotransmitters Through Carbon Nanotubes" (2020). Chemistry Summer Fellows. 31.
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