Submission Date

7-24-2020

Document Type

Paper- Restricted to Campus Access

Department

Chemistry

Faculty Mentor

Mark Ellison

Comments

Presented during the 22nd Annual Summer Fellows Symposium, July 24, 2020 at Ursinus College.

A related presentation is available here.

Project Description

Carbon nanotubes serve as unique nanopore conduits due to their molecular selectivity. In this study we examine the transport of the neurologically relevant molecules acetylcholine, choline, and dopamine through a 1 nm-diameter 1.1-mm long single walled carbon nanotube (SWNT). The pore-blocking threshold voltages were 700 mV, 600 mV, and 500 mV for choline, acetylcholine, and dopamine, respectively. The dwell times for both acetylcholine and choline decrease with increasing voltage which is consistent for the proposed model for these ions. The average dwell times for choline and acetylcholine at 1000mV were 59.59607 ms and 61.96095 ms respectively. The average pore-blocking current (PBC) for choline at 1000 mV was 0.01024 nA and the average PBC for acetylcholine at 1000 mV was 0.023393 nA. At the time of submission of this abstract dopamine data was still undergoing analysis and the results of analysis will be presented in final presentation. Our results show that these three neurotransmitters do transport through a SWNT and the properties can be studied.

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