Submission Date

4-25-2016

Document Type

Paper- Restricted to Campus Access

Department

Chemistry

Second Department

Biology

Adviser

Mark Ellison

Second Adviser

Anthony Lobo

Committee Member

Mark Ellison

Committee Member

Anthony Lobo

Committee Member

Rebecca Evans

Department Chair

Mark Ellison

Department Chair

Peter Small

Project Description

This research examines the use of tetracycline-functionalized single-walled carbon nanotubes to overcome tetracycline resistance in Escherichia coli. The resistant E. coli have the pBR322 resistance plasmid that codes for an efflux pump resistance mechanism. Here, we attempt to block this resistance mechanism by attaching tetracycline to carbon nanotubes in order to recycle previously effective antibiotics for use in resistant bacteria.

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