Human Orthologs of the Ribosome-Associated Complex (RAC) can Functionally Replace the Yeast RAC in S. cerevisiae

Author

Nikole Fandino Pachon, Ursinus CollegeFollow

Submission Date

7-22-2021

Document Type

Paper- Restricted to Campus Access

Department

Biology

Faculty Mentor

Dale Cameron

Second Faculty Mentor

Christina Kelly

Student Contributor

Theodora Zeibekis

Comments

This research was funded by the NIH.

Presented during the 23rd Annual Summer Fellows Symposium, July 23, 2021 at Ursinus College.

Project Description

Proteins are very important for many different functions in our bodies. However, they are prone to misfold, which could make them acquire new toxic functions. In order to prevent these incidents, a special type of proteins called chaperones assist in the proper folding of different proteins. We investigated a special type of chaperones that anchor at the site of protein synthesis, the ribosome, to assist with the proper folding of proteins in yeast. The purpose of this study is to understand if the human version of these chaperones could function in S. cerevisiae.

Recommended Citation

Fandino Pachon, Nikole, "Human Orthologs of the Ribosome-Associated Complex (RAC) can Functionally Replace the Yeast RAC in S. cerevisiae" (2021). Biology Summer Fellows. 86.
https://digitalcommons.ursinus.edu/biology_sum/86