The Regulation of Cathepsin L Activity by Estrogen and Bisphenols A & S: Relationship to Systemic Lupus Erythematosus

Author

Dylan T. Cuva, Ursinus CollegeFollow

Submission Date

4-27-2015

Document Type

Paper

Department

Biology

Adviser

Rebecca Roberts

Committee Member

Rebecca Roberts

Committee Member

Beth Bailey

Committee Member

Eric Williamsen

Department Chair

Kathryn Goddard

Project Description

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that is linked to increased levels of estrogen. Bisphenol A (BPA) is an environmental estrogen that may also play a role in SLE. BPA is used in the production of polycarbonate plastics and epoxy resins, including use in the creation of cans and plastic bottles. This study investigated the role of BPA and other bisphenols on enzyme activity in a murine model for SLE.

Recommended Citation

Cuva, Dylan T., "The Regulation of Cathepsin L Activity by Estrogen and Bisphenols A & S: Relationship to Systemic Lupus Erythematosus" (2015). Biology Honors Papers. 5.
https://digitalcommons.ursinus.edu/biology_hon/5