Submission Date

7-19-2024

Document Type

Paper- Restricted to Campus Access

Department

Biochemistry & Molecular Biology

Faculty Mentor

Eric Williamsen

Comments

Presented during the 26th Annual Summer Fellows Symposium, July 19, 2024 at Ursinus College.

Project Description

The world is in crisis due to excess plastic waste. Each year, 400 tons are produced globally, and with no effective or safe way for their degradation, plastic waste is increasing uncontrollably. The increasing plastic waste is harming animals, ecosystems, and humanity. Previous research suggests that thermophiles, microbes that thrive between 50–140℃, can degrade polyethylene terephthalate (PET), a common plastic, due to their cutinase domains. Chromatographic techniques, techniques that separate mixtures using a mobile and stationary phase, can identify and quantify the rate of degradation of PET. For HPLC (high-performance liquid chromatography), we optimized the flow rate and mobile-phase composition and in GCMS (gas chromatography-mass spectrometry) the temperature programming. We successfully created methods for the separation, detection, and quantification of the enzymatic breakdown products of PET using GCMS (gas chromatography-mass spectrometry) and HPLC.

Restricted

Available to Ursinus community only.

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