Submission Date


Document Type



Health & Exercise Physiology


April Carpenter

Committee Member

Beth Bailey

Committee Member

Nicole Ivaska

Department Chair

Del Engstrom

Project Description

We compared endothelial permeability at 48 hours post skeletal muscle injury in male and female mice at 1 month, 2 months, 3, 6 and 12 months of age. We hypothesized that the female mice would show more permeability at 48 hours post injury than the male mice at all ages. Our findings were more complicated as permeability following injury trends down with age in females, and up with age in males. These findings could be beneficial for medical professionals to tailor an injured athlete’s treatment to their age and sex since there are permeability and therefore possibly inflammation differences.