Submission Date


Document Type

Paper- Restricted to Campus Access



Faculty Mentor

Ryan R. Walvoord


Presented during the 23rd Annual Summer Fellows Symposium, July 23, 2021 at Ursinus College.

Project Description

Chlorite is often present in water as a byproduct of the water purification process. Concentrations of chlorite above the allowed limit can cause damage to red blood cells and is therefore regularly monitored in drinking water sources. Currently, chlorite detection involves advanced instrumentation and off site sample preparation. A potentially simpler and inexpensive detection process may be achieved by fluorogenic probes which undergo a reaction with a specific analyte to have a change in optical properties. Our strategy proposes synthesis and evaluation of a fluorescent probe bearing an aldehyde moiety, which we hypothesize will undergo an oxidation to the carboxylic acid when in the presence of chlorite through a Pinnick oxidation. The probe will be analyzed through spectrophotometry for the change in optical properties.


Available to Ursinus community only.