Submission Date

7-20-2018

Document Type

Paper- Restricted to Campus Access

Department

Chemistry

Faculty Mentor

Ryan Walvoord

Comments

Presented during the 20th Annual Summer Fellows Symposium, July 20, 2018 at Ursinus College.

Project Description

Small molecule fluorescent probes are commonly used in imaging applications and sensors including detecting environmental analytes or elucidating biological phenomena. Many of these compounds function via a change in brightness occurring through photoinduced electron transfer (PeT). Although this concept is well understood, PeT-based probes are almost entirely developed via empirical methods. The current project focuses on synthesizing a series of naphthalene and coumarin-based fluorescent probes bearing carefully altered quenching moieties. The photophysical properties of these molecules will then be determined. Ultimately, this systematic investigation of structure-optical property relationship aims to provide the scientific community with a more rational means for creating these useful chemical tools.

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