Paper- Restricted to Campus Access
Triazines are a group of nitrogen-containing heterocycles, common in pesticides. The run-off of excess pesticides can have major negative impacts on the surrounding environment. Developing probes for these molecules allows for easy and cheap detection of these toxic compounds. Photo induced electron transfer (PET) probes are fluorophores that are 'turned on' when interactions with target molecules adjust the energy levels of the HOMO within the fluorophore inhibiting electronic quenching within the fluorophore. A catalog of characterized fluorophores will allow for a selection of probes with varying accessories tailored for specific triazine molecules. Oxygen and sulfur based fluorophores appear to be species that are reactive with triazine molecules, and have electronics that can be adjusted for higher selectivity. Two sulfur fluorophores, a sulfide and a thioester, have been synthesized and tested for their ability to fluoresce when in the presence of oxidizing agents. The synthesis of different acylated fluorophore compounds have been proposed and more experimentation is needed to gather data on the fluorescence.
Fowler, Erin and St. Jean, Alyssa, "Development of an Oxygen and Sulfur Series of Photo-induced Electron Transfer (PET)-Based Fluorescent Probes for Applications in Triazine Detection" (2020). Chemistry Presentations. 13.
Available to Ursinus community only.