Does Using wee-1.3 as a Secondary Suppressor Restore Wildtype Timing of Meiosis and Oocyte Maturation in pam-1 C. elegans Mutants?
Paper- Restricted to Campus Access
Hugo Moises Montesinos-Yufa
I investigated the relationship between two developmental proteins, PAM-1 and WEE-1.3. WEE-1.3 is an inhibitory kinase that regulates a maturation promoting complex called CDK-1, and is responsible for timely oocyte development. PAM-1 is an aminopeptidase, which cleaves the N terminus of target proteins, and is crucial for polarity establishment, centrosome cortical contact, asymmetrical division, and other developmental markers in a one cell C. elegans embryo. By looking for interactions between the proteins we can better understand developmental processes in C. elegans.
Eisele, Caprice, "Does Using wee-1.3 as a Secondary Suppressor Restore Wildtype Timing of Meiosis and Oocyte Maturation in pam-1 C. elegans Mutants?" (2020). Biology Honors Papers. 34.
This project was funded by the NIH.