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This study hopes to understand the function and possible consequences of prion proteins using Saccharomyces cerevisae and the [PSI+] phenotype as a model. Specifically, this experiment examines prion dependent changes in normal protein expression and in disabled open reading frames (dORFs) such as Pau7 and whether phenotypic changes caused by the [PSI+] prion yields a fitness advantage against normal cells under conditions of extreme environmental stress.
Li, Annie, "Prion-Dependent Changes in Protein Expression in Yeast, Saccharomyces cerevisiae" (2016). Biology Honors Papers. 12.