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This research examines the use of tetracycline-functionalized single-walled carbon nanotubes to overcome tetracycline resistance in Escherichia coli. The resistant E. coli have the pBR322 resistance plasmid that codes for an efflux pump resistance mechanism. Here, we attempt to block this resistance mechanism by attaching tetracycline to carbon nanotubes in order to recycle previously effective antibiotics for use in resistant bacteria.
Force, Madison, "The Use of Tetracycline-Functionalized Single Walled Carbon Nanotubes to Overcome Tetracycline Resistance in Escherichia coli" (2016). Chemistry Honors Papers. 4.