Submission Date

7-22-2016

Document Type

Paper- Restricted to Campus Access

Department

Biochemistry & Molecular Biology

Faculty Mentor

Mark Ellison

Second Faculty Mentor

Anthony Lobo

Comments

Presented during the 18th Annual Summer Fellows Symposium, July 22, 2016 at Ursinus College.

Project Description

With the ever-increasing presence of resistance to available medications new methods of combating infections must be discovered. This research focused on two different microorganisms, Enterococcus faecalis and Saccharomyces cerevisiae, with two different antimicrobials specific to their species, erythromycin and 3,5-dimethylpyrazole-2-methanol for each organism respectively. Using viable cell count, growth curve analysis, and different strains of resistance to the antibiotic in E. faecalis the effects of single-walled carbon nanotubes (SWCNT) on the efficacy of the microbials was investigated in different species as well as in different mechanism models for resistance. Resistant strains of E. faecalis were collected from raw influent at the Oaks sewage treatment plant showing how relevant these microorganisms are for our population as well as how prevalent they are in the gastrointestinal tract of people.

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